We love coffee!
So much that only in this first year of blog, we wrote a few texts related to this wonderful drink, which gives more and more reasons for you to consume it daily! - See more in related posts.
This time the reason for this post is the fresh result of a systematic review and meta-analysis that has confirmed another benefit: consuming high doses of coffee is associated with reducing the risk of Alzheimer's Disease.
The researchers began the study with the hypothesis and data from animal research that caffeine and other bioactive components of coffee could have neuroprotective mechanisms, thereby preventing cognitive decline and dementia.
With the aim of identifying the same results in humans, they evaluated 11 studies (obviously performed only in humans), which fit within the limitations chosen: the studies should be prospective, limited to the consumption of coffee, including total coffee, decaffeinated coffee or coffee with caffeine, with results on cognitive decline, dementia or cognitive impairment, and within a 95% confidence interval.
Thus, the meta-analysis of the 11 studies suggested that coffee, when consumed in high doses, is not associated with a reduction in impairment or cognitive decline or dementia, however, when the results were stratified, it was found that coffee intake is significantly associated with a lower risk for Alzheimer's disease. In addition, habitual coffee consumption has been associated with increased insulin sensitivity and reduced risk of diabetes - considered to be a major risk factor for cognitive decline.
And how much of coffee would be?
It was identified that it would be the equivalent of 500 mg of caffeine or 5 cups / day to achieve this effect.
Important note: this study was performed with coffee, not applying to other drinks containing caffeine. So, because it is a complex blend, and contains, in addition to caffeine, bioavailable polyphenols that can act through numerous mechanisms to produce the beneficial effects observed.
Let's have some coffee?
LIU, Qing-ping et al. Habitual coffee consumption and risk of cognitive decline/dementia: A systematic review and meta-analysis of prospective cohort studies. Nutrition, [s.l.], v. 32, n. 6, p.628-636, jun. 2016. Elsevier BV. http://dx.doi.org/10.1016/j.nut.2015.11.015.